Maspin and MCM2 immunoprofiling in salivary gland carcinomas

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Maspin and MCM2 immunoprofiling in salivary gland carcinomas

BACKGROUND The pathogenesis of salivary gland carcinomas is very complex and prognostic markers are difficult to find in these carcinomas of which the different subtypes have varying malignant potential. The study was conducted to examine the cellular distribution of maspin and MCM2 in salivary gland carcinomas and their value to predict lymph node metastasis. MATERIALS AND METHODS Fifty thre...

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Salivary Gland Carcinomas

Many malignant tumours other than squamous cell carcinoma may present in the oral cavity. Melanomas of the oral cavity are usually pigmented, aggressive tumours associated with a poor prognosis. Neoplasms of the minor salivary glands have a greater tendency to be malignant than those of the major glands, and some exhibit a predilection for occurring in the mouth. Many types of connective tissue...

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Maspin as a tumour suppressor in salivary gland tumour.

Maspin is a protein that belongs to serin protease inhibitor (serpin) superfamily. The purpose of this study was to review the literature concerning the expression of maspin in salivary gland tumours. A literature search was done using MEDLINE, accessed via the National Library of Medicine PubMed interface. Statistical analysis was not done because only seven studies were available in literatur...

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ژورنال

عنوان ژورنال: Diagnostic Pathology

سال: 2011

ISSN: 1746-1596

DOI: 10.1186/1746-1596-6-89